Paroxysmal Nocturnal Hemoglobinuria (PNH) Market to Exhibit Substantial Growth by 2032 – Asserts DelveInsight | AstraZeneca (danicopan/ALXN204), Amgen (ABP 959), Omeros (OMS906), Kira Pharma (KP104)

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Paroxysmal Nocturnal Hemoglobinuria (PNH) Market to Exhibit Substantial Growth by 2032 – Asserts DelveInsight | AstraZeneca (danicopan/ALXN204), Amgen (ABP 959), Omeros (OMS906), Kira Pharma (KP104)

September 20
22:07 2022
Paroxysmal Nocturnal Hemoglobinuria (PNH) Market to Exhibit Substantial Growth by 2032 - Asserts DelveInsight | AstraZeneca (danicopan/ALXN204), Amgen (ABP 959), Omeros (OMS906), Kira Pharma (KP104)
Delveinsight Business Research LLP
As per DelveInsight’s assessment, globally, about 20+ key pharma and biotech companies are working in the Paroxysmal Nocturnal Hemoglobinuria therapeutics landscape based on different Routes of Administration (RoA), Mechanism of Action (MoA), and molecule types. Several of the therapies are in the advanced stages of clinical development and are expected to launch in the coming years.

DelveInsight’s “Paroxysmal Nocturnal Hemoglobinuria (PNH) Market Insights, Epidemiology, and Market Forecast 2032” report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the Paroxysmal Nocturnal Hemoglobinuria Market size, share, and trends in the seven major market (7MM) (i.e., the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan).

The Paroxysmal Nocturnal Hemoglobinuria market report covers emerging drugs, current treatment practices, market share of the individual therapies, and current & forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, key drivers & barriers impacting the market growth, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market. 

Paroxysmal Nocturnal Hemoglobinuria Market

Paroxysmal Nocturnal Hemoglobinuria (PNH): An Overview

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, life-threatening disease of the blood. The disease is characterized by complement-mediated hemolysis with or without hemoglobinuria, increased susceptibility to thrombotic episodes, and/or some degree of bone marrow dysfunction. PNH leads to excessive breakdown of red blood cells, releasing a large amount of hemoglobin into the urine.

The appropriate treatment for PNH depends on the severity of the symptoms. The mainstay of PNH treatment is the drug eculizumab (Soliris).

Paroxysmal Nocturnal Hemoglobinuria (PNH) Market

The market outlook section of the report helps to build a detailed comprehension of the historical, current, and forecasted Paroxysmal Nocturnal Hemoglobinuria market size by analyzing the impact of current and emerging pipeline therapies. It also provides a thorough assessment of the market drivers & barriers, unmet needs, and emerging technologies set to impact the market dynamics.

The report gives complete detail of the Paroxysmal Nocturnal Hemoglobinuria market trend for each marketed drug and mid & late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, their Mechanism of Action (MoA), Route of Administration (RoA), molecule types, competition with other therapies, brand value, and their impact on the market.

Paroxysmal Nocturnal Hemoglobinuria (PNH) Epidemiology

The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted epidemiology trends by exploring numerous studies and research. The epidemiology section also provides a detailed analysis of diagnosed and prevalent patient pool, future trends, and and views of key opinion leaders. 

Paroxysmal Nocturnal Hemoglobinuria (PNH) Drugs Uptake and Pipeline Development Activities

The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Paroxysmal Nocturnal Hemoglobinuria market or expected to get launched during the study period. The analysis covers Paroxysmal Nocturnal Hemoglobinuria market uptake by drugs, patient uptake by therapies, and sales of each drug. 

Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.

The report also covers the Paroxysmal Nocturnal Hemoglobinuria Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyses recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Recent Developments in the Paroxysmal Nocturnal Hemoglobinuria (PNH) Therapeutics Market

• On 16 September 2022, AstraZeneca updated that a prespecified interim analysis of the ALPHA Phase III trial evaluating danicopan (ALXN2040), as an add-on to C5 inhibitor therapy ULTOMIRIS® (ravulizumab-cwvz) or SOLIRIS® (eculizumab) exhibited positive results in patients with paroxysmal nocturnal hemoglobinuria (PNH) who experience clinically significant extravascular hemolysis (EVH).

• On August 23, 2022, Amgen (NASDAQ: AMGN) announced positive top-line results from the DAHLIA Phase 3 study evaluating the efficacy and safety of ABP 959, a biosimilar candidate to SOLIRIS® (eculizumab), compared with SOLIRIS in adult patients with paroxysmal nocturnal hemoglobinuria (PNH).

• In July 2022, Omeros Corporation announced that OMS906 had received orphan drug designation from the US FDA for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). OMS906 is an investigational human monoclonal antibody targeting mannan-binding lectin-associated serine protease-3 (MASP-3), the key activator of the complement system’s alternative pathway.

• In July 2022, Kira Pharmaceuticals announced that the US FDA had granted Orphan Drug Designation to its therapy, KP104, for the treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH).

Learn How Paroxysmal Nocturnal Hemoglobinuria Market Will Evolve by 2032 @

https://www.delveinsight.com/sample-request/paroxysmal-nocturnal-hemoglobinuria-market

Paroxysmal Nocturnal Hemoglobinuria Therapeutics Analysis

There are approx. 20+ key companies which are developing therapies for Paroxysmal Nocturnal Haemoglobinuria. Currently, Hoffman-La-Roche has its Paroxysmal Nocturnal Haemoglobinuria drug candidates in the most advanced stage of clinical development.

Key companies in the Paroxysmal Nocturnal Haemoglobinuria (PNH) Therapeutic Market include:

• Hoffmann-La Roche

• Apellis Pharmaceuticals

• Regeneron Pharmaceuticals

• Biocad

• AKARI Therapeutics

• Alexion Pharmaceuticals

• Novartis Pharmaceuticals

• Amgen

• BioCryst Pharmaceuticals

• MorphoSys

• Ra Pharmaceuticals

• Alnylam Pharmaceuticals

• Arrowhead Pharmaceuticals

• Wuhan Createrna Science and Technology

• CANbridge

• Attune Pharmaceuticals

• RallyBio

 Alexion Pharmaceuticals

And many others

Paroxysmal Nocturnal Haemoglobinuria (PNH) Emerging Drugs Covered in the report include: 

Crovalimab: Hoffman-La-Roche 

Pozelimab: Regeneron Pharmaceuticals

And many more

Further Emerging Drugs & Key Companies are Covered in the Report. Download the Sample PDF to Learn More –

https://www.delveinsight.com/sample-request/paroxysmal-nocturnal-hemoglobinuria-market

Table of Content (TOC)

1. Key Insights

2. Executive Summary 

3. Paroxysmal Nocturnal Hemoglobinuria Competitive Intelligence Analysis

4. Paroxysmal Nocturnal Hemoglobinuria Market Overview at a Glance

5. Paroxysmal Nocturnal Hemoglobinuria Disease Background and Overview

6. Paroxysmal Nocturnal Hemoglobinuria Patient Journey

7. Paroxysmal Nocturnal Hemoglobinuria Epidemiology and Patient Population (In US, EU5, and Japan)

8. Paroxysmal Nocturnal Hemoglobinuria Treatment Algorithm, Current Treatment, and Medical Practices

9. Paroxysmal Nocturnal Hemoglobinuria Unmet Needs

10. Key Endpoints of Paroxysmal Nocturnal Hemoglobinuria Treatment

11. Paroxysmal Nocturnal Hemoglobinuria Marketed Products

12. Paroxysmal Nocturnal Hemoglobinuria Emerging Drugs and Latest Therapeutic Advances

13. Paroxysmal Nocturnal Hemoglobinuria Seven Major Market Analysis

14. Attribute Analysis

15. Paroxysmal Nocturnal Hemoglobinuria Market Outlook (In US, EU5, and Japan)

16. Paroxysmal Nocturnal Hemoglobinuria Access and Reimbursement Overview

17. KOL Views on the Paroxysmal Nocturnal Hemoglobinuria Market

18. Paroxysmal Nocturnal Hemoglobinuria Market Drivers

19. Paroxysmal Nocturnal Hemoglobinuria Market Barriers

20. Appendix

21. DelveInsight Capabilities

22. Disclaimer

*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.

Download Sample PDF to Explore the Key Offerings of the Report: 

https://www.delveinsight.com/sample-request/paroxysmal-nocturnal-hemoglobinuria-market

 

About DelveInsight
DelveInsight is a leading Business Consultant and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance.

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